"Enough is enough is enough," Biden told supporters in Philadelphia.
"Democracy is literally, not figuratively, on the ballot this year," said Biden, who warned about the dangers of extremism in an impassioned speech in Philadelphia last month.
The speech is part of big push by top Democrats to boost Pennsylvania Democrats in the closing stretch ahead of the Nov. 8 midterm election.
"I absolutely do believe that John Fetterman will win this election," Harris told reporters ahead of a speech in Philadelphia.
Trump, Biden's 2020 election opponent potential 2024 adversary, is expected to campaign in Pennsylvania next weekend as well.